In vivo evidence of glutamate toxicity in multiple sclerosis
نویسندگان
چکیده
منابع مشابه
In vivo evidence of glutamate toxicity in multiple sclerosis.
OBJECTIVE There is increasing evidence that altered glutamate (Glu) homeostasis is involved in the pathophysiology of multiple sclerosis (MS). The aim of this study was to evaluate the in vivo effects of excess brain Glu on neuroaxonal integrity measured by N-acetylaspartate (NAA), brain volume, and clinical outcomes in a large, prospectively followed cohort of MS subjects. METHODS We used mu...
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ژورنال
عنوان ژورنال: Annals of Neurology
سال: 2014
ISSN: 0364-5134
DOI: 10.1002/ana.24202